reference standard. Absor 0.0823 0.16 0.268 0.358 0.456 0.572 0.660 0.750 0.836 7 3 5 5 8 Bance Conc. 1.00 2.00 3.00 4.00 5.00 6.00 7.00 8.00 (µg/ml) Table 2: Absorbances of the Ten Brands of Ciprofloxacin hydrochloride Tablets Bran d Code • Ten (10) milligram equivalent of the test samples were weighed and diluted with deionized water to 100ml (100µg/ml stock). The stock, 0.5ml, was diluted to 10ml with deionized water. CF The absorbances of the various brands are shown in Table 2 below: SP AP CB 9.00 CM 0.939 8 CJ 10.00 112 CL CY CG VP Mean 0.502 0.491 0.502 0.509 0.494 0.523 0.451 0.503 0.499 0.500 Abso 0 5 2 0 0 3 3 2 1 113 rbanc Calculate the % Purity of the ciprofloxacin hydrochloride tablet brands using the calibration plot method. (The BP 2005 Specification is 95-105%). (15 Marks).

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